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M94B0806.TXT
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1994-11-11
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Document 0806
DOCN M94B0806
TI Varicella hepatitis: a fatal case in a previously healthy,
immunocompetent adult. Report of a case, autopsy, and review of the
literature.
DT 9412
AU Anderson DR; Schwartz J; Hunter NJ; Cottrill C; Bisaccia E; Klainer AS;
Department of Medicine, Columbia University College of Physicians; and
Surgeons, New York, NY.
SO Arch Intern Med. 1994 Sep 26;154(18):2101-6. Unique Identifier :
AIDSLINE MED/94379883
AB Varicella, usually a benign infection of childhood, is known to be
associated with more serious complications, especially in adults and
immunocompromised patients. Of these, varicella pneumonitis is the most
common. Primary varicella hepatitis has been described, though rarely,
in immunocompromised patients. We present a case of a previously healthy
human immunodeficiency virus-negative 26-year-old immigrant from El
Salvador in whom primary varicella developed that rapidly progressed to
fulminant hepatic failure, disseminated intravascular coagulation, and
death. Autopsy revealed evidence of varicella in the liver, adrenal
glands, and myometrium. To our knowledge, this is the first report of a
fatal case of varicella hepatitis in a previously healthy,
immunocompetent patient.
DE Adult Case Report Chickenpox/*COMPLICATIONS/PATHOLOGY Disseminated
Intravascular Coagulation/MICROBIOLOGY Fatal Outcome Female Hepatic
Encephalopathy/*MICROBIOLOGY/PATHOLOGY Human JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).